Biophysics (BPH)

Section Information

Biophysics focuses on the application of physical principles and quantitative methods to understand biological systems. The field studies the structure, dynamics, and interactions of biomolecules, cells, and tissues using tools from physics, mathematics, and engineering.

Current research explores molecular mechanics, membrane dynamics, protein folding, cellular mechanics, bioenergetics, and structural biology. Advances in imaging, spectroscopy, computational modeling, and single-molecule techniques are expanding knowledge of biological processes at multiple scales.

This section publishes experimental studies, theoretical analyses, quantitative modeling research, instrumentation developments, and review articles related to the physical basis of biological structure and function.

Scope

Molecular Biophysics

• Protein folding and conformational dynamics
• Biomolecular interactions and binding kinetics
• Nucleic acid structure and mechanics
• Single-molecule biophysics techniques

Structural Biophysics

• X-ray crystallography and cryo-electron microscopy
• NMR spectroscopy of biological macromolecules
• Small-angle scattering and structural analysis
• Structure–function relationships

Cellular and Membrane Biophysics

• Membrane structure and transport mechanisms
• Ion channels and electrophysiology
• Cell mechanics and cytoskeletal dynamics
• Mechanobiology and force sensing

Computational and Theoretical Biophysics

• Molecular dynamics simulations
• Statistical mechanics in biological systems
• Modeling of biological networks
• Multiscale simulations of cells and tissues

Imaging and Spectroscopy

• Fluorescence microscopy and super-resolution imaging
• Optical tweezers and force spectroscopy
• Magnetic resonance techniques
• Advanced biophysical instrumentation

Bioenergetics and Metabolic Physics

• Energy conversion in cells
• Mitochondrial function and ATP synthesis
• Thermodynamics of biological reactions
• Physical principles of metabolic regulation

Biomedical and Applied Biophysics

• Biophysical approaches to disease mechanisms
• Drug–target interaction analysis
• Biomaterials and tissue mechanics
• Quantitative diagnostics and medical technologies

Editorial Board

Click here to see the Section Editorial Board of “Biophysics (BPH)”.

Papers Published

Click here to see a list of 3 papers published in this section.