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Keyword: GWASOpen AccessArticle
6 Pages, 995 KB 
Identification of Genetic Variants for Prioritized miRNA-targeted Genes Associated with Complex Traits
Abstract:
Genome-wide association studies, or GWAS, have reported associations between SNPs and specific diseases/traits. GWAS results contain variants located in different genomic regions, including variants in the 3’UTR. MicroRNAs, or miRNAs, are small noncoding RNAs that bind to the 3’UTRs of genes to regulate gene expression. However, variant(s) that are located in the 3’UTR could impact…
Read More(This article belongs to the Special Issue on Innovation in Computing, Engineering Science & Technology 2021 & Section Bioinformatics (BIF))