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Keyword: Sequence alignmentEfficient Alignment of Very Long Sequences
We consider the problem of aligning two very long biological sequences. The score for the best alignment may be found using the Smith-Waterman scoring algorithm while the best alignment itself may be determined using Myers and Miller’s alignment algorithm. Neither of these algorithms takes advantage of computer caches to obtain high efficiency. We propose cache-efficient…
Read MoreHomology Modeling of CYP6Z3 Protein of Anopheles Mosquito
The Anopheles gambiae’s CYP6Z3 protein belongs to the Cytochrome P450 family and functions in oxidation-reduction processes, many studies including our previous work on elucidating insecticide resistance genes of the Anopheles also implicated her in pyrethroid insecticide resistance. Model prediction, functional analysis, and enrichment of the target gene with triplex binding sites may become a useful…
Read MoreEliminating Target Anopheles Proteins to Non-Target Organisms based on Posterior Probability Algorithm
Capturing similarity in gene sequences of a target organism to detect significant regions of comparison will most likely occur because genes share a related descendant. Local sequence alignment for the targeted organisms can help preserve associations among sequences of related organisms. Such homologous genes possess identical sequences with common ancestral genes. The genes may be…
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