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The main purpose in this work is to explore the fact that chaos, as a biological characteristic in the brain, should be used in an Artificial Neural Network (ANN) system. In fact, as long as chaos is present in brain functionalities, its properties need empirical investigations to show their potential to enhance accuracies in artificial…

Despite the significant progress made in data mining technologies in recent years, breast cancer risk prediction and diagnosis at an early stage using DNA microarray technology still a real challenging task. This challenge comes especially from the high-dimensionality in gene expression data, i.e., an enormous number of genes versus a few tens of subjects (samples).…

Cancer is the leading cause of death in world. Currently, there are no approved vaccines to avoid the spreading of this disease. Drug discovery have played important role for discover of new potent drugs that could efficiently and cost-effectively. Pyrazoline analogue compounds known to have good potency as anti-cancer. The aim of this study is…

The increasing number of breast cancer in recent years has attracted numerous researchers’ attention. Several techniques of Computer Aided Diagnosis System have been proposed as alternative solutions to diagnose breast cancer. The flaw of simply using the naked eye to see the differences between normal and with cancer mammogram images makes the texture analysis play…

Breast cancer is one of the most common cancers among female diseases all over the world. Early diagnosis and treatment is particularly important in reducing the mortality rate. This research is focused on the prevention of breast cancer, therefore it is important to detect micro-calcifications (MCs) which are a sign of early stage breast cancer.…

Breast cancer has an important incidence in women mortality worldwide. Currently, mam- mography is considered the gold standard for breast abnormalities screening examinations, since it aids in the early detection and diagnosis of the illness. However, both identification of mass lesions and its malignancy classification is a challenging problem for artificial intelligence. In this work,…

This paper proposes an algorithm aimed at quantifying the expression of KI-67 protein in digital images of breast biopsy tissue samples obtained through an optical microscope. The algorithm allows to obtain a report on the quantity of non-proliferating and proliferating cells through the detection and quantification of KI-67. The sample analysis via software aims to…

An ensemble method is a Machine Learning (ML) algorithm that aggregates the predictions of multiple estimators or models. The purpose of an ensemble module is to provide better predictive performance than any single contributing model. This can be achieved by producing a predictive model with reduced variance using bagging, and bias using boosting. The Tree-Based…