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Keyword: MotifNemoSuite: Web-based Network Motif Analytic Suite
Biological networks represent biological systems, and various graph analysis algorithms have been applied to solve various real-world problems. Network motif analysis, as one of network analyses, is detecting frequently and uniquely over-occurring subgraph patterns in a network. The detection process requires high computational resources, and various tools have been developed to provide efficient solutions. However,…
Read MoreNemoMap: Improved Motif-centric Network Motif Discovery Algorithm
Network motif analysis has several applications in many different fields such as biological study and social network modeling, yet motif detection tools are still limited by the intensive computation. Currently, there are two categories for network motif detection method: network-centric and motif-centric approach. While most network-centric algorithms excel in enumerating all potential motifs of a…
Read MoreGC4miRNA - a Pipeline for Examining Impact of GC Content in miRNA Seed Sequences on Expression in Tumor Samples
MicroRNAs (miRNAs) are small RNA molecules that play a crucial role in regulating gene expression by binding to and degrading targeted mRNAs. miRNAs targeting a specific mRNA have a region known as the “seed sequence”, which typically has a high affinity for its complementary sequence in the targeted mRNA. Single Nucleotide Polymorphisms (SNPs) are mutations…
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