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Keyword: SNP
Dissection of Quantitative Trait Loci (QTL), Annotation of Single Nucleotide Polymorphism (SNP), and Identification of Candidate Genes for Grain Yield in Triticum turgidum L. var durum
Durum wheat (Triticum turgidum L. var durum) is among the most important crops in the world. High and stable grain yield in diverse environments is the major objective in durum breeding programs. This trait is linked to the quantitative trait loci (QTL). For the detection of QTL linked to the grain yield, it is necessary…
Read More GC4miRNA - a Pipeline for Examining Impact of GC Content in miRNA Seed Sequences on Expression in Tumor Samples
MicroRNAs (miRNAs) are small RNA molecules that play a crucial role in regulating gene expression by binding to and degrading targeted mRNAs. miRNAs targeting a specific mRNA have a region known as the “seed sequence”, which typically has a high affinity for its complementary sequence in the targeted mRNA. Single Nucleotide Polymorphisms (SNPs) are mutations…
Read More Identification of Genetic Variants for Prioritized miRNA-targeted Genes Associated with Complex Traits
Genome-wide association studies, or GWAS, have reported associations between SNPs and specific diseases/traits. GWAS results contain variants located in different genomic regions, including variants in the 3’UTR. MicroRNAs, or miRNAs, are small noncoding RNAs that bind to the 3’UTRs of genes to regulate gene expression. However, variant(s) that are located in the 3’UTR could impact…
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