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Keyword: Bioinformatics
GC4miRNA - a Pipeline for Examining Impact of GC Content in miRNA Seed Sequences on Expression in Tumor Samples
MicroRNAs (miRNAs) are small RNA molecules that play a crucial role in regulating gene expression by binding to and degrading targeted mRNAs. miRNAs targeting a specific mRNA have a region known as the “seed sequence”, which typically has a high affinity for its complementary sequence in the targeted mRNA. Single Nucleotide Polymorphisms (SNPs) are mutations…
Read More Efficient Discretization Approaches for Machine Learning Techniques to Improve Disease Classification on Gut Microbiome Composition Data
The human gut environment can contain hundreds to thousands bacterial species which are proven that they are associated with various diseases. Although Machine learning has been supporting and developing metagenomic researches to obtain great achievements in personalized medicine approaches to improve human health, we still face overfitting issues in Bioinformatics tasks related to metagenomic data…
Read More Discovering Interesting Biological Patterns in the Context of Human Protein-Protein Interaction Network and Gene Disease Profile Data
The current advances in proteomic and transcriptomic technologies produced huge amounts of high-throughput data that spans multiple biological processes and characteristics in different organisms. One of the important directions in today’s bioinformatics research is to discover patterns of genes that have interesting properties. These groups of genes can be referred to as functional modules. Detecting…
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