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MicroRNAs (miRNAs) are small RNA molecules that play a crucial role in regulating gene expression by binding to and degrading targeted mRNAs. miRNAs targeting a specific mRNA have a region known as the “seed sequence”, which typically has a high affinity for its complementary sequence in the targeted mRNA. Single Nucleotide Polymorphisms (SNPs) are mutations…

In the Internet of Things era it is expected that low-end processor domination of the embedded market will be further reaffirmed. Then, a question will arise, on whether it is possible to enhance performance of such processors without the cost of high-end architectures. In this work we propose a better-than-worst-case (BTWC) methodology which enables the…

Degradation measurements are often treated and analyzed for improvement the reliability of system. Our objective in this paper is to study a class of non linear systems, whose dynamics and observations are non linear functions of the state. Obviously, we develop an Extended Kalman Filtering (EKF) algorithm for detecting the additive failures in a two…

The purpose of this paper is to improve the thermographic method for detection the places of heat energy losses on the urban underground thermal pipelines using the computer system. This goal was achieved by building a heat map of the surveyed heating main with data layering directly on a computer map of the area, which…

We address irregular polygon nesting on sheet materials with a lightweight evolutionary framework that operates directly in the layout space. The method formalizes multi-term fitness combining utilization, overlap penalties, spacing regularity, and local alignment, with all components normalized before aggregation. Feasibility is enforced by an AABB– SAT pipeline and validated via analytic ground-truth cases, degenerate…

Cyber security is based on different principles such as confidentiality and integrity of transmitted data. One of the main methods to send confidential messages is to use a shared secret to encrypt and decrypt them. Even if the amortized computational complexity of the hashing functions is Ο(1), there are several situations when it is not…

The efficient processing of database applications on computing systems with multi-tiered persistent storage devices needs specialized algorithms to create optimal persistent storage management plans. A correct allocation and deallocation of multi-tiered persistent storage may significantly improve the overall performance of data processing. This paper describes the new algorithms that create allocation and deallocation plans for…

Genome-wide association studies, or GWAS, have reported associations between SNPs and specific diseases/traits. GWAS results contain variants located in different genomic regions, including variants in the 3’UTR. MicroRNAs, or miRNAs, are small noncoding RNAs that bind to the 3’UTRs of genes to regulate gene expression. However, variant(s) that are located in the 3’UTR could impact…

Quantum computers are heterogeneous device. It consists of a main CPU and a quantum accelerator. True quantum accelerator (or coprocessor) is analog and probabilistic device. Qubits are the basic building blocks of quantum computers. But qubits can be digital. A digital qubit is similar to RISC processor pipeline and is an unique chain of digital…

3D city modeling may be considered as one of the key applications, that are provided by the Automated Feature Extraction (AFE) techniques from LiDAR data. The authors attempt to prove that with growing availability of LiDAR surveying methods the resulted 3D city models become the most significant modeled features for any urban environment. Our paper…

During service, oil and gas pipelines may be exposed to cyclical loads during service, which may lead to a structural failure. Failure is due in most cases to cracks in the structure. Mechanics of the propagation of surface cracks pose a serious challenge and, therefore, models are required to help analyze it. In this study,…

The paper discusses the features of the implementation and functioning of digital self-timed circuits. They have a naturally high tolerance to short-term single soft errors caused by various factors, such as nuclear particles, radiation, and others. Combinational self-timed circuits using dual-rail coding of signals are naturally immune to 91% of typical soft errors classified in…

Vision-based defect detection techniques are widely used for quality control purposes. In this work, an efficient deflectometry based detection system is developed for semi-specular/painted surface defect detection. This system consists of a robotic arm that carries a screen/camera setup and can detect defects on large surfaces with different topologies, such as a car bumper, by…

This work presents new pipeline-parallel, generic and configurable parallel hardware architectures for the Direct/Inverse Wavelet Packet Transform (DWPT/IDWPT) independent of any specific family of wavelets, implemented in FPGA technology using a parallel architecture of direct FIR filter. We propose in the following paper, new P-parallel structures for the DWPT and IDWPT transforms based on the…

This article is devoted to the problem of blocking the propagation of sound in a gas stream. This can be useful in the problems of pipeline acoustics and the design of automotive silencers, when it is necessary to ensure the opacity of the boundary (cross section of the pipe) for sound simultaneously with the free…

New multimedia applications such as mobile video, high-quality Internet video or digital television requires high-performance encoding of video signals to meet technical constraints such as runtime, bandwidth or latency. Video coding standard h.265 HEVC (High Efficiency Video Coding) was developed by JCT-VC to replace the MPEG-2, MPEG-4 and h.264 codecs and to respond to these…

This work is dedicated to present a new pipeline-parallel architecture of Discrete Wavelet Packet Transform (DWPT) for all wavelet family implemented in FPGA technology. The main target of our architecture is to provide an effective performance trade-off, where it significantly increases the throughput with a restricted amount of hardware. In this article, we propose two…