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Section: bifGC4miRNA - a Pipeline for Examining Impact of GC Content in miRNA Seed Sequences on Expression in Tumor Samples
MicroRNAs (miRNAs) are small RNA molecules that play a crucial role in regulating gene expression by binding to and degrading targeted mRNAs. miRNAs targeting a specific mRNA have a region known as the “seed sequence”, which typically has a high affinity for its complementary sequence in the targeted mRNA. Single Nucleotide Polymorphisms (SNPs) are mutations…
Read MoreInvestigating Heart Rate Variability Index Classification in Macaca fascicularis and Humans: Exploring Applications for Personal Identification and Anonymization Studies
In this paper, we determine the feasibility of differentiating between the heart rate patterns of Macaca fascicularis and human infants by comparing pertinent hyperparameters. This verification process was undertaken to ascertain the suitability of Macaca fascicularis heart rate data as a testbed for evaluating heart rate parameter privacy safeguarding methodologies. The biological characteristics of Macaca…
Read MoreA Secure Medical History Card Powered by Blockchain Technology
A reliable healthcare system ensures that the population has access to top-notch medical ser- vices, ultimately enhancing their overall health most efficiently. At times, data are not secured or handled appropriately. Addressing these concerns, blockchain technology is projected to bring about a substantial revolution in the medical industry by assuring the confidentiality of electronic health…
Read MoreComparative Study of J48 Decision Tree and CART Algorithm for Liver Cancer Symptom Analysis Using Data from Carnegie Mellon University
Liver cancer is a major contributor to cancer-related mortality both in the United States and worldwide. A range of liver diseases, such as chronic liver disease, liver cirrhosis, hepatitis, and liver cancer, play a role in this statistic. Hepatitis, in particular, is the main culprit behind liver cancer. As a consequence, it is decisive to…
Read MoreSmart Healthcare Kit for Domestic Purposes
The COVID-19 pandemic has caused a substantial death toll throughout the world. The pandemic has created a threat to public health, the economy, food systems, and the workplace. An increased reprioritization of health expenditure towards COVID-19 vaccines will impact on allocations to other medical facilities. In developing countries, hospitals shortage the infrastructure to facilitate patients.…
Read MoreA Cloud Telemedicine Platform Based on Workflow Management System: A Review of an Italian Case Study
The paper aims to describe a new technological and organizational approach in order to manage teleconsultation and telemonitoring processes involving a Physician, who remotely interacts with one or more Specialists, in order to evaluate and discuss the specific clinical conditions of a patient, based primarily on the sharing of digital clinical data, reports and diagnostic…
Read MoreInterpretable Rules Using Inductive Logic Programming Explaining Machine Learning Models: Case Study of Subclinical Mastitis Detection for Dairy Cows
With the development of Internet of Things technology and the widespread use of smart devices, artificial intelligence is now being applied as a decision-making tool in a variety of fields. To make machine learning models, including deep neural network models, more interpretable, various techniques have been proposed. In this paper, a method for explaining the…
Read MoreIdentification of Genetic Variants for Prioritized miRNA-targeted Genes Associated with Complex Traits
Genome-wide association studies, or GWAS, have reported associations between SNPs and specific diseases/traits. GWAS results contain variants located in different genomic regions, including variants in the 3’UTR. MicroRNAs, or miRNAs, are small noncoding RNAs that bind to the 3’UTRs of genes to regulate gene expression. However, variant(s) that are located in the 3’UTR could impact…
Read MoreDevelopment of an EEG Controlled Wheelchair Using Color Stimuli: A Machine Learning Based Approach
Brain-computer interface (BCI) has extensively been used for rehabilitation purposes. Being in the research phase, the brainwave based wheelchair controlled systems suffer from several limitations, e.g., lack of focus on mental activity, complexity in neural behavior in different conditions, and lower accuracy. Being sensitive to the color stimuli, the EEG signal changes promises a better…
Read MoreAnalysis of qCON and qNOX Anesthesia Indices and EEG Spectral Energy during Natural Sleep Stages
The objective of this research is to study the behaviour of the anaesthesia monitor Conox during natural sleep to open the gate for this devices to assess subjects during this stage. The values of qCON and qNOX indices and EEG frequency bands are analysed during night sleep of 10 volunteers when they lose consciousness, in…
Read MorePerformance Evaluation of a Gamified Physical Rehabilitation Balance Platform through System Usability and Intrinsic Motivation Metrics
Motivation significantly influences the outcome in the rehabilitation of patients. Several developments have been made to assess and increase patient motivation by addressing factors linked to motivation such as the personality of the patient, professional administering rehabilitation, and the rehabilitation environment. The main objective of the study is to evaluate the reliability of a gamified…
Read MoreDiagnosis of Tobacco Addiction using Medical Signal: An EEG-based Time-Frequency Domain Analysis Using Machine Learning
Addiction such as tobacco smoking affects the human brain and thus causes significant changes in the brainwaves. The changes in brain wave due to smoking can be identified by focusing on changes in electroencephalogram pattern, extracting different time-frequency domain features. In this aspect, a laboratory-based study has been presented in this paper, for assessing the…
Read MoreSupervised Learning Techniques for Stress Detection in Car Drivers
In this paper we propose the application of supervised learning techniques to recognize stress situations in drivers by analyzing their Skin Potential Response (SPR) and the Electrocardiogram (ECG). A sensing device is used to acquire the SPR from both hands of the drivers, and the ECG from their chest. We also consider a motion artifact…
Read MoreTolerance of Characteristics and Attributes in Developing Student’s Academic Achievements
The purpose of this research is to study the relevance of factors for the analysis of the effectiveness of suitable educational institutions that illustrate the significance of the characteristics and attributes of the student’s academic achievements and to identify the acceptance and tolerance of each attribute, which supports lifelong learning. The data used in this…
Read MoreThe Design Process in the Improvement of The Experience Between a Brand and its Target Audience Through a Digital Product: The Lexus Portugal’s used Car Website Case Study
The study aims to demonstrate how the use of the design process can align a brand’s strategy with the interests of its target audience through a digital product based on a case study. Currently, Lexus internal studies show that there is a possibility to meet the needs of new audiences, beyond the traditional ones (men,…
Read MoreCNN-LSTM Based Model for ECG Arrhythmias and Myocardial Infarction Classification
ECG analysis is commonly used by medical practitioners and cardiologists for monitoring cardiac health. A high-performance automatic ECG classification system is a challenging area because there is difficulty in detecting and clustering various waveforms in the signal, especially in the manual analysis of electrocardiogram (ECG) signals. In this paper, an accurate (ECG) classification and monitoring…
Read MoreInterpretation of Machine Learning Models for Medical Diagnosis
Machine learning has been dramatically advanced over several decades, from theory context to a general business and technology implementation. Especially in healthcare research, it is obvious to perceive the scrutinizing implementation of machine learning to warranty the rewarded benefits in early disease detection and service recommendation. Many practitioners and researchers have eventually recognized no absolute…
Read MoreA Hybrid Mod
The ability to verify the critical risk factors related to an effective diagnosis is very crucial for improving accuracy on coronary heart disease prediction. The objective of this research is to find the best predictive model for coronary heart disease diagnosis. Three approaches are set up to achieve the goals (1) investigating the classifier algorithms…
Read MoreDifferential Evolution based Hyperparameters Tuned Deep Learning Models for Disease Diagnosis and Classification
With recent advancements in medical filed, the quantity of healthcare care data is increasing at a faster rate. Medical data classification is considered as a major research topic and numerous research works have been already existed in the literature. Presently, deep learning (DL) models offers an efficient method for developing a dedicated model to determine…
Read MoreConvolutional Neural Network Based Classification of Patients with Pneumonia using X-ray Lung Images
Analysis and classification of lung diseases using X-ray images is a primary step in the procedure of pneumonia diagnosis, especially in a critical period as pandemic of COVID-19 that is type of pneumonia. Therefore, an automatic method with high accuracy of classification is needed to perform classification of lung diseases due to the increasing number…
Read MoreAssessing the Operator’s Readiness to Perform Tasks of Controlling by the Unmanned Aerial Platforms
Together with the intensity of development in the field of technology of unmanned platforms and their effective use for solving various tasks of peacetime and war, the requirements for the training of the operator managing the platform also increase. This fully applies to personnel providing the flight of manned means. Nevertheless, there are significant differences…
Read MoreComposition of Methods to Ensure Iris Liveness and Authenticity
In a biometric system technology, a person is authenticated based on processing the unique features of the human biometric signs. One of the well known biometric systems is iris recognition, this technique being considered as one of the most secure authentication solutions in the biometric field. However, several attacks do exist that are able to…
Read MoreDesign of an EEG Acquisition System for Embedded Edge Computing
The human brain is one of the most complex machines on the planet. Being the only method to get real-time data with high temporal resolution from the brain makes EEG a highly sought upon signal in the neurological and psychiatric domain. However, recent developments in this field have made EEG more than just a tool…
Read MoreActiverest: Design of A Graphical Interface for the Remote use of Continuous and Holistic Care Providers
One of the most prevalent physical limitations of both aging and accidents is immobility. Being bedridden requires great care to avoid the formation of pressure ulcers. Thus, the ‘ActiveRest’ project aimed to develop a textile mattress guard that will contribute to the prevention of pressure ulcers. This textile mattress guard integrates a monitoring system, based…
Read MoreThe Usability Evaluation of Academic Progress Information System (SIsKA-NG)
Limited functionalities of the Academic Progress Information System (SIsKA) has direct consequences on the quality of thesis management service at the authors’ magister study program of the authors’ university. This research focused on the significant improvement from the previous User Experience Questionnaire (UEQ) result of SIsKA. That significant improvement was based on the recommendations from…
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